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EPM - Equine Protozoal Myeloencephalitis

Equine Protozoal Myeloencephalitis (EPM) is a disease that affects the horse's spinal cord and brain. It is caused by a protozoa which is a parasite that infests several bird species, including cowbirds and grackles. Opossums are the normal host animals, although the parasite must pass through a bird before completing its life cycle in the opossum.

EPM mimics many other neurological conditions. However, the neurological symptoms associated with EPM can include the following:


  • Lameness or weakness
  • A lack of coordination and difficulty in moving
  • A loss of balance
  • Seizures

Current Therapies for Horses with EPM

The use of Karbo Combo® has, in field studies, proven very effective in resolving the symptoms of EPM.

Karbo Combo® consists of encapsulated enzymes, vitamins, bacteria and large numbers of mannan and glucan oligosaccharides. In addition, the formula also contains glycocomponents necessary for tying up and neutralizing various toxins.

The objective of Karbo Combo® is to attach and bind to the surface lectins of pathogenic viruses, bacteria, ptotozoa and toxins, therefore rendering them incapable of colonization and reproduction.

Click here for information on the supplement Karbo Combo®

Karbo Combo®
Recommended amount of Karbo Combo®
for horses with EPM:
Animal Weight Amount Frequency
Foals 1/2 ounce AM&PM
400# 1/2 ounce AM&PM
600# 3/4 ounce AM&PM
800# 1 ounce AM&PM
1000# 1 1/2 ounces AM&PM
1500# 2 ounces AM&PM
Follow this schedule for 60 days, then continue feeding at the maintenance level
(1/2 the regular amount once per day.)
Buy 3 and save $25. Click for more details.
Size Price Savings Current Stock Select Quantity Add to Cart
5 pounds Reg. $125
$115 		Save $10
10 pounds Reg. $250
$240		 Save $10
20 pounds Reg. $500
$470		 Save $30




Disclaimer: The Statements on this web site have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure, or prevent any disease.